I dont think that HRT "changes" sexuality. But that it can/does bring out what may be hidden just under the surface,. As I mentioned I previously already, had an interest/curiosity in male genitals, and had even an experience w few times w a male friend when I was younger, but never thought of myself as Gay or even Bi. Fast forward 45 years,, Starting Estrogen didnt change my sexuality. But I have a theory about what did happen. It was when I started Progesterone; That did two things: It worked as desired to increase my boobs from B to Ds. AND, it made me somewhat , "baby crazy" wanting to get pregnant. Ive heard this same thing from a few other Gurls too. I think my brain is saying, ok so you want to have a baby? You better go out and find a GUY first,, ;) I also wonder if my Orchiectomy added to this as it makes me look and feel so much more feminine,,. Just my take on this,. I love knowing that a guy is attracted to me and is turned on by me. Because that in turn, turns ME on as well. Call it simply validation if you like, but it works for me :) The first time that I was w/ a guy as a woman it just totally lit a fire in me that still burns :) This is way more TMI than I had intended, but I feel this is a topic that too often gets swept under the rug,. I also know that when I finally get my vagina, Im going to put it to some very good use ;)